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Are you looking for adventure and a complete change of scene? A cruise in South America is what you need. The continent is exceptional and each country has  surprises in store for you! Your sea cruise will be a unique opportunity to discover the splendid landscapes of Latin America. Between the fjords in Chile, the white sandy beaches in Mexico, the volcanoes in Nicaragua or Chile, you will have many memories that you will share with your loved one back in France! It will also be an opportunity  to enrich your cultural experience with the many archaeological sites located throughout the continent. Perhaps you will have the chance to cross the Panama Canal. Finally, one thing is certain, you will be amazed by the beauty of the fauna and flora, notably the multicolored parrots and the famous Peruvian llamas.

Departure Months

September 2026
October 2026
November 2026
December 2026
January 2027
February 2027
March 2027
April 2027
May 2027
September 2027
October 2027
November 2027
December 2027
January 2028
February 2028
March 2028
April 2028
November 2028
December 2028
January 2029
February 2029
267 Cruises Refine

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South America : Brazil - MSC Virtuosa

Itinerary : Salvador, Maceió, Santos Sao Paulo, Búzios, Salvador

South America : Brazil - MSC Virtuosa

From $200

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Salvador Duration : 8 Days
  • Duration : 8 Days From $200
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $200

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Departures :

8-15-22 December 26
5-12-19-26 January 27
2-9-16-23 February 27
2-9-16-23 March 27
7-14 December 27
11-18-25 January 28
1-8-15-22-29 February 28
7-14 March 28

8-15-22 December 26

Other departures

South America : Brazil - MSC Virtuosa

Itinerary : Salvador, Maceió, Santos Sao Paulo, Rio de Janeiro, Búzios, Salvador

South America : Brazil - MSC Virtuosa

From $210

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Salvador Duration : 9 Days
  • Duration : 9 Days From $210
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $210

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Departure :

21 March 28

21 March 28

South America : Brazil - MSC Virtuosa

Itinerary : Maceió, Santos Sao Paulo

South America : Brazil - MSC Virtuosa

From $309

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club

From $309

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Departures :

23 December 26
31 March 27

23 December 26

31 March 27

Transoceanic : Brazil - MSC Divina

Itinerary : Santos Sao Paulo, Rio de Janeiro, Salvador

Transoceanic : Brazil - MSC Divina

From $339

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $339
  • Boat : MSC Divina
  • Company : MSC Cruises

From $339

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Departure :

14 March 27

14 March 27

Transoceanic : Brazil, Canary Islands, Morocco, Spain - MSC Virtuosa

Itinerary : Santos Sao Paulo, Rio de Janeiro, Búzios, Salvador, Maceió, Santa Cruz de Tenerife, Tanger, Barcelone

Transoceanic : Brazil, Canary Islands, Morocco, Spain - MSC Virtuosa

From $350

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 18 Days
  • Duration : 18 Days From $350
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $350

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Departures :

3 April 27
25 March 28

3 April 27

25 March 28

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Musica

From $359

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $359
  • Boat : MSC Musica
  • Company : MSC Cruises

From $359

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Departures :

3-10 December 26
19 March 27
24 November 27
3 December 27

3-10 December 26

19 March 27

Other departures

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Musica

From $359

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $359
  • Boat : MSC Musica
  • Company : MSC Cruises

From $359

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Departures :

20-23-30 November 26
17 December 26
29 March 27
27-30 November 27
6-13 December 27

20-23-30 November 26

Other departures

South America : Brazil - MSC Virtuosa

Itinerary : Salvador, Maceió, Santos Sao Paulo

South America : Brazil - MSC Virtuosa

From $391

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Salvador Duration : 5 Days
  • Duration : 5 Days From $391
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $391

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Departure :

30 March 27

30 March 27

South America : Brazil, Portugal - MSC Musica

Itinerary : Rio de Janeiro, Búzios, Ilha Grande, Paranagua

South America : Brazil, Portugal - MSC Musica

From $399

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Rio de Janeiro Duration : 5 Days
  • Duration : 5 Days From $399
  • Boat : MSC Musica
  • Company : MSC Cruises

From $399

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Departure :

9 March 27

9 March 27

South America : Brazil - MSC Divina

Itinerary : Santos Sao Paulo, Angra dos Reis, Búzios, Santos Sao Paulo

South America : Brazil - MSC Divina

From $399

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $399
  • Boat : MSC Divina
  • Company : MSC Cruises

From $399

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Departure :

18 December 26

18 December 26

South America : Brazil - MSC Meraviglia

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Meraviglia

From $409

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $409
  • Boat : MSC Meraviglia
  • Company : MSC Cruises

From $409

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Departures :

25 November 27
30 March 28
6-9-16 April 28

25 November 27

30 March 28

Other departures

South America : Brazil - MSC Divina

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Divina

From $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $419
  • Boat : MSC Divina
  • Company : MSC Cruises

From $419

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Departures :

29 January 27
12-19-22 February 27
1-8 March 27
4-11-18 February 28
3-10 March 28

29 January 27

Other departures

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Búzios, Ilha Grande, Santos Sao Paulo

South America : Brazil - MSC Musica

From $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $419
  • Boat : MSC Musica
  • Company : MSC Cruises

From $419

Discover Offer

Departures :

26 November 26
6 December 26
9 December 27

26 November 26

6 December 26

Other departures

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Búzios, Porto Belo, Santos Sao Paulo

South America : Brazil - MSC Musica

From $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $419
  • Boat : MSC Musica
  • Company : MSC Cruises

From $419

Discover Offer

Departure :

16 December 27

16 December 27

South America : Brazil - MSC Divina

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Divina

From $449

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $449
  • Boat : MSC Divina
  • Company : MSC Cruises

From $449

Discover Offer

Departures :

15-26 December 26
2-23 January 27
9 February 27
11 March 27
29 February 28
13-16 March 28

15-26 December 26

Other departures

South America : Brazil - MSC Virtuosa

Itinerary : Santos Sao Paulo, Búzios, Salvador

South America : Brazil - MSC Virtuosa

From $463

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $463
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $463

Discover Offer

Departure :

5 December 26

5 December 26

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Ilha Grande, Ilhabela, Santos Sao Paulo

South America : Brazil - MSC Musica

From $479

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $479
  • Boat : MSC Musica
  • Company : MSC Cruises

From $479

Discover Offer

Departure :

16 November 26

16 November 26

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Búzios, Ilha Grande, Santos Sao Paulo

South America : Brazil - MSC Musica

From $479

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $479
  • Boat : MSC Musica
  • Company : MSC Cruises

From $479

Discover Offer

Departures :

13 December 26
22 March 27

13 December 26

22 March 27

South America : Brazil - MSC Virtuosa

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Virtuosa

From $479

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $479
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $479

Discover Offer

Departure :

2 December 26

2 December 26

South America : Brazil - MSC Musica

Itinerary : Santos Sao Paulo, Búzios, Ilha Grande, Santos Sao Paulo

South America : Brazil - MSC Musica

From $479

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $479
  • Boat : MSC Musica
  • Company : MSC Cruises

From $479

Discover Offer

Departure :

15 March 27

15 March 27

South America : Brazil - MSC Meraviglia

Itinerary : Santos Sao Paulo, Búzios, Ilha Grande, Santos Sao Paulo

South America : Brazil - MSC Meraviglia

From $479

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $479
  • Boat : MSC Meraviglia
  • Company : MSC Cruises

From $479

Discover Offer

Departures :

2-12 April 28

2-12 April 28

South America : Brazil - MSC Divina

Itinerary : Santos Sao Paulo, Búzios, Porto Belo, Santos Sao Paulo

South America : Brazil - MSC Divina

From $499

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $499
  • Boat : MSC Divina
  • Company : MSC Cruises

From $499

Discover Offer

Departures :

23 January 28
14 February 28

23 January 28

14 February 28

South America : Brazil - MSC Divina

Itinerary : Santos Sao Paulo, Búzios, Ilha Grande, Santos Sao Paulo

South America : Brazil - MSC Divina

From $499

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $499
  • Boat : MSC Divina
  • Company : MSC Cruises

From $499

Discover Offer

Departures :

1-15 February 27
31 January 28
7-21-25 February 28
6 March 28

1-15 February 27

Other departures

South America : Brazil - MSC Virtuosa

Itinerary : Santos Sao Paulo, Búzios, Salvador, Maceió

South America : Brazil - MSC Virtuosa

From $501

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 5 Days
  • Duration : 5 Days From $501
  • Boat : MSC Virtuosa
  • Company : MSC Cruises

From $501

Discover Offer

Departures :

5 December 26
2 January 27

5 December 26

2 January 27

South America : Brazil - MSC Seaview

Itinerary : Santos Sao Paulo, Búzios, Santos Sao Paulo

South America : Brazil - MSC Seaview

From $509

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Santos Sao Paulo Duration : 4 Days
  • Duration : 4 Days From $509
  • Boat : MSC Seaview
  • Company : MSC Cruises

From $509

Discover Offer

Departure :

29 November 26

29 November 26

What is the best period to go on a  cruise in South America?

So, you're probably wondering when to book your cruise in Latin America? You should know that it is in winter that you will fully enjoy your trip. The climate is mild and very pleasant. Your excursions to Rio de Janeiro in Brazil, Venezuela or Chile will be unforgettable! Hikers who want to tackle the Andes, the longest mountain range in the world, should go there in late spring, when the sun is shining and temperatures are pleasant.

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