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Your Mediterranean cruise promises to be sunny! Several dream itineraries are available. Indeed, the Mediterranean rim covers many countries and coastlines where it is possible to embark on a cruise ship: Morocco, Algeria, Tunisia, Egypt, Israel, Cyprus, Turkey, Greece, Albania, Montenegro, Croatia, Slovenia, Malta, Italy, Monaco, France, Gibraltar and Spain.

As an intercontinental sea, it is home to many different cultures, religions and lifestyles, which makes your adventure more exotic. You go on a cruise with the promise of a colorful journey! From one port of call to another, you will discover the beauty of a new environment, a new climate, a new art, a new way of thinking, a new way of living of a civilization, you will observe the traditions or the heritage... It is the ideal destination to leave on a cruise trip alone, as a couple, with your family or with friends...

Departure Months

June 2025
July 2025
August 2025
September 2025
October 2025
November 2025
December 2025
January 2026
February 2026
March 2026
April 2026
May 2026
June 2026
July 2026
August 2026
September 2026
October 2026
November 2026
December 2026
January 2027
February 2027
March 2027
April 2027
May 2027
June 2027
July 2027
August 2027
September 2027
October 2027
November 2027

Departure Ports

Marseille
Genoa
Savone
Toulon
Cannes
Barcelone
Venise
Athens Le Piree
Trieste
Rome Civitavecchia
Nice
Istanbul
411 Cruises Refine

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Mediterranean : Spain, France, Italy - MSC Splendida

Itinerary : Barcelone, Marseille, Genoa, Naples

Mediterranean : Spain, France, Italy - MSC Splendida

From $289
-26% $213

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 4 Days
  • Duration : 4 Days From $289 -26% $213
  • Boat : MSC Splendida
  • Company : MSC Cruises

From $289 -26% $213

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Departure :

7 February 26

7 February 26

Mediterranean : Italy, Greece - MSC Fantasia

Itinerary : Trieste, Katakolon, Athens Le Piree

Mediterranean : Italy, Greece - MSC Fantasia

From $309
-25% $233

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Trieste Duration : 4 Days
  • Duration : 4 Days From $309 -25% $233
  • Boat : MSC Fantasia
  • Company : MSC Cruises

From $309 -25% $233

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Departure :

3 May 26

3 May 26

Mediterranean : Italy, France, Spain - MSC Opera

Itinerary : Genoa, Marseille, Malaga

Mediterranean : Italy, France, Spain - MSC Opera

From $339
-24% $259

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Genoa Duration : 4 Days
  • Duration : 4 Days From $339 -24% $259
  • Boat : MSC Opera
  • Company : MSC Cruises

From $339 -24% $259

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Departure :

13 May 26

13 May 26

Mediterranean : Turkey, Greece, Italy - MSC Sinfonia

Itinerary : Istanbul, Corfu, Bari

Mediterranean : Turkey, Greece, Italy - MSC Sinfonia

From $349
-22% $273

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Istanbul Duration : 4 Days
  • Duration : 4 Days From $349 -22% $273
  • Boat : MSC Sinfonia
  • Company : MSC Cruises

From $349 -22% $273

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Departure :

6 May 26

6 May 26

Mediterranean : Spain, France, Italy - MSC Euribia

Itinerary : Barcelone, Marseille, Genoa, Naples

Mediterranean : Spain, France, Italy - MSC Euribia

From $349
-22% $273

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 4 Days
  • Duration : 4 Days From $349 -22% $273
  • Boat : MSC Euribia
  • Company : MSC Cruises

From $349 -22% $273

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Departure :

24 October 26

24 October 26

Mediterranean : Italy, France - MSC Magnifica

Itinerary : Rome Civitavecchia, Genoa, Marseille, Genoa

Mediterranean : Italy, France - MSC Magnifica

From $429
-33% $289

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Rome Civitavecchia Duration : 4 Days
  • Duration : 4 Days From $429 -33% $289
  • Boat : MSC Magnifica
  • Company : MSC Cruises

From $429 -33% $289

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Departure :

12 December 25

12 December 25

Mediterranean : Spain, France, Italy - MSC Grandiosa

Itinerary : Valence, Marseille, Genoa, Rome Civitavecchia

Mediterranean : Spain, France, Italy - MSC Grandiosa

From $369
-21% $293

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Valence Duration : 4 Days
  • Duration : 4 Days From $369 -21% $293
  • Boat : MSC Grandiosa
  • Company : MSC Cruises

From $369 -21% $293

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Departure :

25 September 25

25 September 25

Mediterranean : Italy, France - MSC Orchestra

Itinerary : Cagliari, Rome Civitavecchia, Genoa, Marseille, Livourne

Mediterranean : Italy, France - MSC Orchestra

From $419
-26% $311

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Cagliari Duration : 5 Days
  • Duration : 5 Days From $419 -26% $311
  • Boat : MSC Orchestra
  • Company : MSC Cruises

From $419 -26% $311

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Departure :

9 November 25

9 November 25

Mediterranean : Spain, France, Italy - MSC Splendida

Itinerary : Barcelone, Marseille, Genoa, Barcelone

Mediterranean : Spain, France, Italy - MSC Splendida

From $399
-20% $319

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 4 Days
  • Duration : 4 Days From $399 -20% $319
  • Boat : MSC Splendida
  • Company : MSC Cruises

From $399 -20% $319

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Departure :

5 November 25

5 November 25

Mediterranean : Italy, France, Spain - MSC Magnifica

Itinerary : Genoa, Marseille, Barcelone, Rome Civitavecchia, Genoa

Mediterranean : Italy, France, Spain - MSC Magnifica

From $529
-40% $319

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Genoa Duration : 6 Days
  • Duration : 6 Days From $529 -40% $319
  • Boat : MSC Magnifica
  • Company : MSC Cruises

From $529 -40% $319

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Departure :

15 December 25

15 December 25

Mediterranean : Italy, France, Spain - MSC Musica

Itinerary : Olbia, Genoa, Marseille, Barcelone

Mediterranean : Italy, France, Spain - MSC Musica

From $409
-19% $333

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Olbia Duration : 4 Days
  • Duration : 4 Days From $409 -19% $333
  • Boat : MSC Musica
  • Company : MSC Cruises

From $409 -19% $333

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Departure :

1 November 25

1 November 25

Mediterranean : Italy, France, Spain - MSC Grandiosa

Itinerary : Genoa, Marseille, Barcelone, Genoa

Mediterranean : Italy, France, Spain - MSC Grandiosa

From $449
-22% $349

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Genoa Duration : 5 Days
  • Duration : 5 Days From $449 -22% $349
  • Boat : MSC Grandiosa
  • Company : MSC Cruises

From $449 -22% $349

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Departure :

15 November 25

15 November 25

Mediterranean : Spain, Italy, France - MSC Grandiosa

Itinerary : Barcelone, Genoa, Marseille, Barcelone

Mediterranean : Spain, Italy, France - MSC Grandiosa

From $449
-22% $349

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 5 Days
  • Duration : 5 Days From $449 -22% $349
  • Boat : MSC Grandiosa
  • Company : MSC Cruises

From $449 -22% $349

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Departure :

17 November 25

17 November 25

Mediterranean : Italy, Spain, France - MSC Splendida

Itinerary : Genoa, Barcelone, Marseille, Genoa

Mediterranean : Italy, Spain, France - MSC Splendida

From $449
-22% $349

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Genoa Duration : 5 Days
  • Duration : 5 Days From $449 -22% $349
  • Boat : MSC Splendida
  • Company : MSC Cruises

From $449 -22% $349

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Departures :

21-25 October 25
3 November 25

21-25 October 25

3 November 25

Mediterranean : France, Italy, Spain - MSC Splendida

Itinerary : Marseille, Genoa, Barcelone, Marseille

Mediterranean : France, Italy, Spain - MSC Splendida

From $449
-22% $349

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Marseille Duration : 5 Days
  • Duration : 5 Days From $449 -22% $349
  • Boat : MSC Splendida
  • Company : MSC Cruises

From $449 -22% $349

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Departures :

20-24 October 25
2 November 25

20-24 October 25

2 November 25

Mediterranean : Italy, Spain, France - MSC Splendida

Itinerary : Genoa, Barcelone, Marseille, Genoa

Mediterranean : Italy, Spain, France - MSC Splendida

From $489
-29% $349

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Genoa Duration : 4 Days
  • Duration : 4 Days From $489 -29% $349
  • Boat : MSC Splendida
  • Company : MSC Cruises

From $489 -29% $349

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Departure :

7 November 25

7 November 25

Mediterranean : Spain, France, Italy - MSC Euribia

Itinerary : Barcelone, Marseille, Genoa, Naples, Palermo

Mediterranean : Spain, France, Italy - MSC Euribia

From $469
-23% $361

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 5 Days
  • Duration : 5 Days From $469 -23% $361
  • Boat : MSC Euribia
  • Company : MSC Cruises

From $469 -23% $361

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Departure :

24 October 26

24 October 26

Mediterranean : France, Spain, Italy - MSC Grandiosa

Itinerary : Marseille, Barcelone, Genoa, Marseille

Mediterranean : France, Spain, Italy - MSC Grandiosa

From $479
-21% $379

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Marseille Duration : 5 Days
  • Duration : 5 Days From $479 -21% $379
  • Boat : MSC Grandiosa
  • Company : MSC Cruises

From $479 -21% $379

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Departure :

16 November 25

16 November 25

Mediterranean : Italy, Croatia - MSC Fantasia

Itinerary : Trieste, Zadar, Dubrovnik, Bari

Mediterranean : Italy, Croatia - MSC Fantasia

From $459
-17% $383

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Trieste Duration : 4 Days
  • Duration : 4 Days From $459 -17% $383
  • Boat : MSC Fantasia
  • Company : MSC Cruises

From $459 -17% $383

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Departure :

29 October 25

29 October 25

Mediterranean : France, Italy - MSC Seaview

Itinerary : Marseille, Genoa, Rome Civitavecchia, Ajaccio, Marseille

Mediterranean : France, Italy - MSC Seaview

From $499
-20% $399

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Marseille Duration : 5 Days
  • Duration : 5 Days From $499 -20% $399
  • Boat : MSC Seaview
  • Company : MSC Cruises

From $499 -20% $399

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Departure :

13 November 26

13 November 26

Mediterranean : Spain, France, Italy - MSC Splendida

Itinerary : Barcelone, Marseille, Genoa, Barcelone

Mediterranean : Spain, France, Italy - MSC Splendida

From $509
-20% $409

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 5 Days
  • Duration : 5 Days From $509 -20% $409
  • Boat : MSC Splendida
  • Company : MSC Cruises

From $509 -20% $409

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Departures :

19-23 October 25
1 November 25

19-23 October 25

1 November 25

Mediterranean : France, Italy, Spain - MSC Orchestra

Itinerary : Marseille, Genoa, Livourne, Rome Civitavecchia, Valence, Barcelone, Marseille

Mediterranean : France, Italy, Spain - MSC Orchestra

From $599
-30% $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Marseille Duration : 8 Days
  • Duration : 8 Days From $599 -30% $419
  • Boat : MSC Orchestra
  • Company : MSC Cruises

From $599 -30% $419

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Departures :

17-24 November 25
1-8-15-22-29 December 25
5-12-19-26 January 26
2-9-16-23 February 26
2-9-16-23-30 March 26
6-13 April 26
9-23-30 November 26
7-14-21-28 December 26
4-11-18-25 January 27
1-8-15 February 27
15-22-29 March 27
5 April 27

17-24 November 25

Other departures

Mediterranean : Italy, Spain, France - MSC Orchestra

Itinerary : Livourne, Rome Civitavecchia, Valence, Barcelone, Marseille, Genoa, Livourne

Mediterranean : Italy, Spain, France - MSC Orchestra

From $599
-30% $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Livourne Duration : 8 Days
  • Duration : 8 Days From $599 -30% $419
  • Boat : MSC Orchestra
  • Company : MSC Cruises

From $599 -30% $419

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Departures :

19-26 November 25
3-10-17-24-31 December 25
7-14-21-28 January 26
4-11-18-25 February 26
4-11-18-25 March 26
1-8-15 April 26
2-9-16-23-30 December 26
6-13-20-27 January 27
3-10-17 February 27
17-24-31 March 27
7 April 27

19-26 November 25

Other departures

Mediterranean : Spain, France, Italy - MSC Orchestra

Itinerary : Barcelone, Marseille, Genoa, Livourne, Rome Civitavecchia, Valence, Barcelone

Mediterranean : Spain, France, Italy - MSC Orchestra

From $599
-30% $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Barcelone Duration : 8 Days
  • Duration : 8 Days From $599 -30% $419
  • Boat : MSC Orchestra
  • Company : MSC Cruises

From $599 -30% $419

Discover Offer

Departures :

16-23-30 November 25
7-14-21-28 December 25
4-11-18-25 January 26
1-8-15-22 February 26
1-8-15-22-29 March 26
5-12 April 26
8-22-29 November 26
6-13-20-27 December 26
3-10-17-24-31 January 27
7-14 February 27
14-21-28 March 27
4 April 27

16-23-30 November 25

Other departures

Mediterranean : Italy, Spain, France - MSC Orchestra

Itinerary : Genoa, Livourne, Rome Civitavecchia, Valence, Barcelone, Marseille, Genoa

Mediterranean : Italy, Spain, France - MSC Orchestra

From $599
-30% $419

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Genoa Duration : 8 Days
  • Duration : 8 Days From $599 -30% $419
  • Boat : MSC Orchestra
  • Company : MSC Cruises

From $599 -30% $419

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Departures :

18-25 November 25
2-9-16-23-30 December 25
6-13-20-27 January 26
3-10-17-24 February 26
3-10-17-24-31 March 26
7-14 April 26
10-24 November 26
1-8-15-22-29 December 26
5-12-19-26 January 27
2-9-16 February 27
16-23-30 March 27
6 April 27

18-25 November 25

Other departures

What to do on your Mediterranean cruise?

The Mediterranean Sea and its ports of call are home to many treasures to explore. Many of the ports of departure are themselves places that deserve your full attention. So why not stay here to start your cruise on the right foot and get into the rhythm of the Dolce Vita?

Marseille, for example, is one of France's leading ports hosting a large number of cruise ships. The city is known for its old port, its cathedral "La bonne mère" perched on the heights, its endless creeks covered with charismatic pine trees and hosting translucent turquoise waters, not to mention its cuisine offering delicious seafood specialties.

Rome (Civitavecchia) is also an ideal cruise port to start your holiday. Rome is La Dolce Vita in the true sense of the word, with its history, architectural and cultural heritage, and Italian specialities, everything is there for you to enjoy during a stopover or a stay before your departure.

Barcelona, the Catalan capital, is an authentic and friendly place in Spain. Known for its typical narrow streets, its monuments with original and meticulous architecture, a Latin atmosphere that warms the hearts... This is a city not to be missed during a Mediterranean cruise!

A cruise in the Mediterranean means magnificent ports of call, but it is also the opportunity to spend days at sea relaxing and enjoying yourself on board the cruise ship of your choice, taking advantage of a multitude of activities and services. It can also be the possibility of appreciating the journey at sea by observing the horizon and the maritime environment that surrounds you, or of being dazzled by a unique sunset reflected in the ship's wake...

A unique feeling of freedom will overwhelm you thanks to this atypical way of travel.

Companies that sail across the Mediterranean :

There are many and for good reason : The Mediterranean is one of tourist’s favorite destinations thanks to its mix of culture and wonderful weather!

Costa Cruises and MSC Cruises are the leading cruise operators in this destination. They offer a wide choice of itineraries and numerous departure dates throughout the year. Their fleet is made up of large cruise ships with a wide range of facilities and infrastructures, offering optimal comfort and a high quality of service.

Some companies also specialize in Mediterranean cruises, such as Celestyal Cruises, which sets sails for the Eastern Mediterranean (It is up to you to discover the Greek islands!). They use their expertise to make you discover places of unsuspected beauty.

You can choose a sailboat cruise  in the Mediterranean: the famous 5-mats Club Med for a cruise departing from Nice in a festive atmosphere. Or try the Ponant ship for a luxury cruise with unrivaled comfort... Finally, try the adventure on board the ships of the Starclippers company for an authentic and warm experience in the shoes of a real sailor!

All the other cruise lines that offer you dream cruises in the Mediterranean:

Azamara Club Cruise, Celebrity Cruises, CroisiMer, Crystal Cruises, Cunard, Holland America Line, Norwegian Cruise Line, Oceania Cruises, Plein Cap Croisière, Ponant, Princess Cruises, Pullmantur, Regent Seven Seas, Rivage du monde, Royal Caribbean International, Seabourn Cruise Line, SeaDream Yacht Club, Silversea Cruises...

Each company is unique and offers different services according to your expectations. It is up to you to select THE cruise that will make you dream and will offer you the itinerary that suits you the most.

What is the best time to go on a Mediterranean cruise?

The Mediterranean climate is mild and temperate all year round. This means that you can take a Mediterranean cruise in winter without fear of too low temperatures and enjoy all the cultural activities and visits that are available to you. The Mediterranean winter is mild and not very humid.

Summer, from June to September, is dry and hot. It has the ideal temperatures for a relaxing trip, with a programme full of beach days, swimming and sunbathing. Be sure to stay well hydrated!

The Indian summer in the Mediterranean extends the mildness during the months of September and October. During these months, the sun and high temperatures are always present. The landscapes start to take on their autumnal colors, for magnificent panoramas.

The low season' period is between November and April. During this period you can get the best cruise fares.

Because of the almost ubiquitous good weather and mild temperatures, a Mediterranean cruise is an opportunity for travelers to relax and pamper themselves. Your days will be punctuated by beaches, naps in the sun, sunbathing sessions, water games and water sports.

Safircruise makes you discover all the cruises in the Mediterranean from a multitude of ports. Select the cruise that will make your stay unforgettable!

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