Panama Canal is one of the main maritime trade routes and is located in Central America. The canal is no less than 77km long. It passes through the Isthmus of Panama, which is located between the Caribbean Sea and the Pacific Ocean. This canal also links two oceans, the Atlantic and the Pacific. In 1914, the Panama Canal was opened to free circulation, thus provoking a real revolution in navigation.

Your Panama Canal cruise will take you to beautiful countries such as Colombia, Honduras, Mexico, Panama and Costa Rica. In addition, you will feel like a true traveler as you sail in the wake of famous navigators such as Vasco Núñez de Balboa. Most of the time, the cruises will leave from big cities in the United States like Miami, Los Angeles or from South American cities like San Jose in Costa Rica.

You will be charmed by the beauty of Panama. From its colorful mosaics to its nuanced landscapes, let yourself be transported on an unforgettable escapade where you will discover natural phenomena such as the Baru volcano. From up there, you can enjoy the best view in Panama. 

Departure Months

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Panama Canal : Panama, Costa Rica, Mexico, United States - Serenade of the Seas

Itinerary : Colon, Puntarenas, Huatulco, Puerto Vallarta, Los Angeles

Panama Canal : Panama, Costa Rica, Mexico, United States - Serenade of the Seas

From $353

Full board
Full board Port taxes included

From $353

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Departure :

25 April 26

Panama Canal : United States, Mexico, Guatemala, Costa Rica, Colombia, Jamaica, Cayman Islands - Celebrity Summit

Itinerary : Los Angeles, Puerto Vallarta, Port Quetzal, Puntarenas, Carthagène, Ocho Rios, George Town, Tampa

Panama Canal : United States, Mexico, Guatemala, Costa Rica, Colombia, Jamaica, Cayman Islands - Celebrity Summit

From $711

Full board
Full board All Included Offer Available

From $711

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Departure :

1 October 26

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $779

Full board
Full board Port taxes included

From $779

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2-23 January 28

Other departures

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

From $779

Full board
Full board Port taxes included

From $779

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $779

Full board
Full board Port taxes included

From $779

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17 January 27

19 December 27

Other departures

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

From $809

Full board
Full board Port taxes included

From $809

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Departure :

9 January 28

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $879

Full board
Full board Port taxes included

From $879

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Departure :

19 March 28

Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Kralendijk, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas

From $889

Full board
Full board Port taxes included

From $889

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Departure :

14 February 27

Caribbean-Antilles : Colombia, Bonaire, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Kralendijk, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Bonaire, Aruba, Curacao, Panama - Grandeur of the Seas

From $919

Full board
Full board Port taxes included

From $919

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Departures :

6 September 26

2 April 28

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

Itinerary : Miami, Ocho Rios, Carthagène, Colon, Limon Port, Roatan, Belize, Miami

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

From $939

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 12 Days
  • Duration : 12 Days From $939
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $939

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

Itinerary : Miami, Montego Bay, Carthagène, Colon, Limon Port, Roatan, Belize, Miami

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

From $959

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 12 Days
  • Duration : 12 Days From $959
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $959

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3-24 January 27

23 January 28

Caribbean-Antilles : Colombia, Curacao, Bonaire, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Kralendijk, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Bonaire, Aruba, Panama - Grandeur of the Seas

From $1,050

Full board
Full board Port taxes included

From $1,050

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Departures :

14-28 March 27

Caribbean-Antilles : Colombia, Aruba, Bonaire, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Kralendijk, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Bonaire, Curacao, Panama - Grandeur of the Seas

From $1,050

Full board
Full board Port taxes included

From $1,050

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Departure :

11 April 27

Caribbean-Antilles : Colombia, Bonaire, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Kralendijk, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Bonaire, Curacao, Aruba, Panama - Grandeur of the Seas

From $1,117

Full board
Full board Port taxes included

From $1,117

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Departure :

24 January 27

Caribbean-Antilles : Colombia, Curacao, Aruba, Bonaire, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Kralendijk, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Bonaire, Panama - Grandeur of the Seas

From $1,129

Full board
Full board Port taxes included

From $1,129

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Departure :

31 January 27

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

Itinerary : Miami, Carthagène, Colon, Puntarenas, Cabo San Lucas, San Diego, Los Angeles, Seattle

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

From $1,989
-42% $1,159

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 19 Days
  • Duration : 19 Days From $1,989 -42% $1,159
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,989 -42% $1,159

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Departure :

23 April 26

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

Itinerary : Miami, Carthagène, Colon, Puntarenas, Cabo San Lucas, San Diego

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

From $1,569
-22% $1,219

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 14 Days
  • Duration : 14 Days From $1,569 -22% $1,219
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,569 -22% $1,219

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Departure :

23 April 26

Panama Canal : United States, Mexico, Guatemala, Costa Rica, Colombia, Cayman Islands - Serenade of the Seas

Itinerary : San Diego, Puerto Vallarta, Port Quetzal, Puntarenas, Carthagène, George Town, Tampa

Panama Canal : United States, Mexico, Guatemala, Costa Rica, Colombia, Cayman Islands - Serenade of the Seas

From $1,306

Full board
Full board Port taxes included

From $1,306

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Departure :

7 October 27

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

Itinerary : Miami, Carthagène, Colon, Puntarenas, Cabo San Lucas, San Diego, Los Angeles

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

From $1,689
-22% $1,309

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 15 Days
  • Duration : 15 Days From $1,689 -22% $1,309
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,689 -22% $1,309

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Departure :

23 April 26

Panama Canal : United States, Aruba, Curacao, Panama, Cayman Islands, Bahamian -

Itinerary : Fort Lauderdale Miami, Oranjestad, Willemstad, Colon, George Town, Bimini Islands, Fort Lauderdale Miami

Panama Canal : United States, Aruba, Curacao, Panama, Cayman Islands, Bahamian -

From $1,403

Full board
Full board All Included Offer Available
  • Departure Port : Fort Lauderdale Miami Duration : 12 Days
  • Duration : 12 Days From $1,403
  • Boat :
  • Company : Celebrity Cruises

From $1,403

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22 November 27

3 January 28

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

Itinerary : Seattle, Los Angeles, San Diego, Cabo San Lucas, Puntarenas, Colon, Carthagène, Miami

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

From $1,519

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Seattle Duration : 20 Days
  • Duration : 20 Days From $1,519
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,519

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Departure :

28 September 26

Panama Canal : United States, Bahamian, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands - Norwegian Sun

Itinerary : Miami, Great Stirrup Cay, Carthagène, Colon, Limon Port, Falmouth, George Town, Miami

Panama Canal : United States, Bahamian, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands - Norwegian Sun

From $1,537

Full board
Full board Port taxes included All Inclusive available

From $1,537

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Departures :

18-29 November 26

Panama Canal : United States, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico - Norwegian Sun

Itinerary : Miami, Falmouth, Carthagène, Colon, Limon Port, Harvest Cay, Cozumel, Miami

Panama Canal : United States, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico - Norwegian Sun

From $1,538

Full board
Full board Port taxes included All Inclusive available

From $1,538

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10 December 26

2 January 27

Other departures

Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Kralendijk, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas

From $1,561

Full board
Full board Port taxes included

From $1,561

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Departure :

20 December 26

Transoceanic : United States, Colombia, Panama, Mexico - MSC Poesia

Itinerary : Miami, Carthagène, Colon, Huatulco, Cabo San Lucas, San Diego, Los Angeles, Seattle

Transoceanic : United States, Colombia, Panama, Mexico - MSC Poesia

From $1,569

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 19 Days
  • Duration : 19 Days From $1,569
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,569

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Departure :

8 April 27

What is the best period to cruise the Panama Canal?

With tropical temperatures, it will be pleasant to spend a cruise on the Panama Canal. Temperatures are often around 30°C, so you can tan easily. The period from January to April is the dry season. It is during this period that it is best to go on a cruise on the Panama Canal. The period from September to December is rainy so we recommend you to avoid it.