Panama Canal is one of the main maritime trade routes and is located in Central America. The canal is no less than 77km long. It passes through the Isthmus of Panama, which is located between the Caribbean Sea and the Pacific Ocean. This canal also links two oceans, the Atlantic and the Pacific. In 1914, the Panama Canal was opened to free circulation, thus provoking a real revolution in navigation.
Your Panama Canal cruise will take you to beautiful countries such as Colombia, Honduras, Mexico, Panama and Costa Rica. In addition, you will feel like a true traveler as you sail in the wake of famous navigators such as Vasco Núñez de Balboa. Most of the time, the cruises will leave from big cities in the United States like Miami, Los Angeles or from South American cities like San Jose in Costa Rica.
You will be charmed by the beauty of Panama. From its colorful mosaics to its nuanced landscapes, let yourself be transported on an unforgettable escapade where you will discover natural phenomena such as the Baru volcano. From up there, you can enjoy the best view in Panama.
Sort by :
Panama Canal : Panama, United States, Costa Rica, Mexico - Serenade of the Seas
Itinerary : Colon, Los Angeles, Puntarenas, Huatulco, Puerto Vallarta
Panama Canal : Panama, United States, Costa Rica, Mexico - Serenade of the Seas
- Departure Port : Colon
-
Duration : 10 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $466
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas
Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $667
Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas
Itinerary : Carthagène, Oranjestad, Kralendijk, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $735
Caribbean-Antilles : Colombia, Curacao, Aruba, Bonaire, Panama - Grandeur of the Seas
Itinerary : Carthagène, Willemstad, Oranjestad, Kralendijk, Colon, Carthagène
Caribbean-Antilles : Colombia, Curacao, Aruba, Bonaire, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $755
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas
Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $755
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas
Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $779
Caribbean-Antilles : Colombia, Bonaire, Curacao, Aruba, Panama - Grandeur of the Seas
Itinerary : Carthagène, Kralendijk, Willemstad, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Bonaire, Curacao, Aruba, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $805
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas
Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $809
Caribbean-Antilles : Colombia, Curacao, Bonaire, Aruba, Panama - Grandeur of the Seas
Itinerary : Carthagène, Willemstad, Kralendijk, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Curacao, Bonaire, Aruba, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $844
Caribbean-Antilles : Colombia, Aruba, Bonaire, Curacao, Panama - Grandeur of the Seas
Itinerary : Carthagène, Oranjestad, Kralendijk, Willemstad, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Bonaire, Curacao, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $854
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas
Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $879
Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas
Itinerary : Carthagène, Oranjestad, Kralendijk, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $886
Panama Canal : United States, Guatemala, Mexico, Cayman Islands, Colombia, Panama, Costa Rica - Celebrity Summit
Itinerary : Fort Lauderdale Miami, Port Quetzal, Puerto Vallarta, Mazatlan, Los Angeles, George Town, Carthagène, Colon, Puntarenas
Panama Canal : United States, Guatemala, Mexico, Cayman Islands, Colombia, Panama, Costa Rica - Celebrity Summit
- Departure Port : Fort Lauderdale Miami
-
Duration : 17 Days
![]()
- Boat : Celebrity Summit of Celebrity Cruises
From $892
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Serenade of the Seas
Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Serenade of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $893
Panama Canal : United States, Colombia, Jamaica, Cayman Islands, Mexico, Guatemala, Costa Rica - Celebrity Summit
Itinerary : Los Angeles, Carthagène, Ocho Rios, George Town, Tampa, Puerto Vallarta, Port Quetzal, Puntarenas
Panama Canal : United States, Colombia, Jamaica, Cayman Islands, Mexico, Guatemala, Costa Rica - Celebrity Summit
- Departure Port : Los Angeles
-
Duration : 17 Days
![]()
- Boat : Celebrity Summit of Celebrity Cruises
From $910
Caribbean-Antilles : Colombia, Bonaire, Aruba, Curacao, Panama - Grandeur of the Seas
Itinerary : Carthagène, Kralendijk, Oranjestad, Willemstad, Colon, Carthagène
Caribbean-Antilles : Colombia, Bonaire, Aruba, Curacao, Panama - Grandeur of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $919
Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia
Itinerary : Miami, Ocho Rios, Carthagène, Colon, Limon Port, Roatan, Belize, Miami
Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia
- Departure Port : Miami
-
Duration : 12 Days
![]()
- Boat : MSC Poesia of MSC Cruises
From $939
Caribbean-Antilles : Panama, Bonaire, Aruba, Curacao, Trinidad and Tobago - Grandeur of the Seas
Itinerary : Colon, Colon, Kralendijk, Oranjestad, Willemstad, Port of Spain, Scarborough
Caribbean-Antilles : Panama, Bonaire, Aruba, Curacao, Trinidad and Tobago - Grandeur of the Seas
- Departure Port : Colon
-
Duration : 10 Days
![]()
- Boat : Grandeur of the Seas of Royal Caribbean International
From $949
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Serenade of the Seas
Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Serenade of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $1,029
Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia
Itinerary : Miami, Montego Bay, Carthagène, Colon, Limon Port, Roatan, Belize, Miami
Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia
- Departure Port : Miami
-
Duration : 12 Days
![]()
- Boat : MSC Poesia of MSC Cruises
From $1,039
Caribbean-Antilles : Colombia, Bonaire, Aruba, Panama - Serenade of the Seas
Itinerary : Carthagène, Kralendijk, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Bonaire, Aruba, Panama - Serenade of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $1,069
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Serenade of the Seas
Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Serenade of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $1,162
Caribbean-Antilles : Colombia, Bonaire, Aruba, Panama - Serenade of the Seas
Itinerary : Carthagène, Kralendijk, Oranjestad, Colon, Carthagène
Caribbean-Antilles : Colombia, Bonaire, Aruba, Panama - Serenade of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $1,179
Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Bahamian - MSC Divina
Itinerary : Miami, Ocho Rios, Carthagène, Colon, Limon Port, Roatan, MSC Ocean Cay Marine Reserve, Miami
Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Bahamian - MSC Divina
- Departure Port : Miami
-
Duration : 12 Days
![]()
- Boat : MSC Divina of MSC Cruises
From $1,789
-33%
$1,199
Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Serenade of the Seas
Itinerary : Carthagène, Oranjestad, Kralendijk, Colon, Carthagène
Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Serenade of the Seas
- Departure Port : Carthagène
-
Duration : 7 Days
![]()
- Boat : Serenade of the Seas of Royal Caribbean International
From $1,211
