Panama Canal is one of the main maritime trade routes and is located in Central America. The canal is no less than 77km long. It passes through the Isthmus of Panama, which is located between the Caribbean Sea and the Pacific Ocean. This canal also links two oceans, the Atlantic and the Pacific. In 1914, the Panama Canal was opened to free circulation, thus provoking a real revolution in navigation.

Your Panama Canal cruise will take you to beautiful countries such as Colombia, Honduras, Mexico, Panama and Costa Rica. In addition, you will feel like a true traveler as you sail in the wake of famous navigators such as Vasco Núñez de Balboa. Most of the time, the cruises will leave from big cities in the United States like Miami, Los Angeles or from South American cities like San Jose in Costa Rica.

You will be charmed by the beauty of Panama. From its colorful mosaics to its nuanced landscapes, let yourself be transported on an unforgettable escapade where you will discover natural phenomena such as the Baru volcano. From up there, you can enjoy the best view in Panama. 

Departure Months

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Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $856

Full board
Full board Port taxes included

From $856

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17 January 27

19 December 27

Other departures

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $856

Full board
Full board Port taxes included

From $856

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23 January 28

27 February 28

Other departures

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

From $856

Full board
Full board Port taxes included

From $856

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

From $917

Full board
Full board Port taxes included

From $917

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Departure :

9 January 28

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $937

Full board
Full board Port taxes included

From $937

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Departures :

2 January 28

19 March 28

Caribbean-Antilles : Colombia, Bonaire, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Kralendijk, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Bonaire, Aruba, Curacao, Panama - Grandeur of the Seas

From $977

Full board
Full board Port taxes included

From $977

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Departures :

6 September 26

2 April 28

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

Itinerary : Miami, Ocho Rios, Carthagène, Colon, Limon Port, Roatan, Belize, Miami

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

From $999

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 12 Days
  • Duration : 12 Days From $999
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $999

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

Itinerary : Seattle, Los Angeles, San Diego, Cabo San Lucas, Puntarenas, Colon, Carthagène, Miami

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

From $1,229
-15% $1,049

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Seattle Duration : 20 Days
  • Duration : 20 Days From $1,229 -15% $1,049
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,229 -15% $1,049

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Departure :

28 September 26

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Curacao, Panama - Grandeur of the Seas

From $1,057

Full board
Full board Port taxes included

From $1,057

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20 December 26

31 January 27

Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Kralendijk, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Bonaire, Panama - Grandeur of the Seas

From $1,061

Full board
Full board Port taxes included

From $1,061

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Departure :

14 February 27

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Aruba, Panama - Grandeur of the Seas

From $1,091

Full board
Full board Port taxes included

From $1,091

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Departure :

24 January 27

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

Itinerary : Miami, Montego Bay, Carthagène, Colon, Limon Port, Roatan, Belize, Miami

Caribbean : United States, Jamaica, Colombia, Panama, Costa Rica, Honduras, Belize - MSC Poesia

From $1,109

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 12 Days
  • Duration : 12 Days From $1,109
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,109

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3-24 January 27

23 January 28

Caribbean-Antilles : Colombia, Curacao, Bonaire, Aruba, Panama - Grandeur of the Seas

Itinerary : Carthagène, Willemstad, Kralendijk, Oranjestad, Colon, Carthagène

Caribbean-Antilles : Colombia, Curacao, Bonaire, Aruba, Panama - Grandeur of the Seas

From $1,215

Full board
Full board Port taxes included

From $1,215

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Departures :

14-28 March 27

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

Itinerary : San Diego, Cabo San Lucas, Puntarenas, Colon, Carthagène, Miami

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

From $1,259

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : San Diego Duration : 15 Days
  • Duration : 15 Days From $1,259
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,259

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Departure :

3 October 26

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

Itinerary : Los Angeles, San Diego, Cabo San Lucas, Puntarenas, Colon, Carthagène, Miami

Transoceanic : United States, Mexico, Costa Rica, Panama, Colombia - MSC Poesia

From $1,269

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Los Angeles Duration : 16 Days
  • Duration : 16 Days From $1,269
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,269

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Departure :

2 October 26

Panama Canal : United States, Aruba, Curacao, Panama, Cayman Islands, Bahamian -

Itinerary : Fort Lauderdale Miami, Oranjestad, Willemstad, Colon, George Town, Bimini Islands, Fort Lauderdale Miami

Panama Canal : United States, Aruba, Curacao, Panama, Cayman Islands, Bahamian -

From $1,389

Full board
Full board All Included Offer Available
  • Departure Port : Fort Lauderdale Miami Duration : 12 Days
  • Duration : 12 Days From $1,389
  • Boat :
  • Company : Celebrity Cruises

From $1,389

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22 November 27

3 January 28

Caribbean-Antilles : Colombia, Aruba, Bonaire, Curacao, Panama - Grandeur of the Seas

Itinerary : Carthagène, Oranjestad, Kralendijk, Willemstad, Colon, Carthagène

Caribbean-Antilles : Colombia, Aruba, Bonaire, Curacao, Panama - Grandeur of the Seas

From $1,427

Full board
Full board Port taxes included

From $1,427

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Departure :

11 April 27

Panama Canal : United States, Mexico, Guatemala, Costa Rica, Colombia, Cayman Islands - Serenade of the Seas

Itinerary : San Diego, Puerto Vallarta, Port Quetzal, Puntarenas, Carthagène, George Town, Tampa

Panama Canal : United States, Mexico, Guatemala, Costa Rica, Colombia, Cayman Islands - Serenade of the Seas

From $1,437

Full board
Full board Port taxes included

From $1,437

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Departure :

7 October 27

Transoceanic : United States, Colombia, Panama, Mexico - MSC Poesia

Itinerary : Miami, Carthagène, Colon, Huatulco, Cabo San Lucas, San Diego, Los Angeles, Seattle

Transoceanic : United States, Colombia, Panama, Mexico - MSC Poesia

From $1,459
-1% $1,439

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 19 Days
  • Duration : 19 Days From $1,459 -1% $1,439
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,459 -1% $1,439

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Departure :

8 April 27

Panama Canal : United States, Bahamian, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands - Norwegian Sun

Itinerary : Miami, Great Stirrup Cay, Carthagène, Colon, Limon Port, Falmouth, George Town, Miami

Panama Canal : United States, Bahamian, Colombia, Panama, Costa Rica, Jamaica, Cayman Islands - Norwegian Sun

From $1,537

Full board
Full board Port taxes included All Inclusive available

From $1,537

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Departures :

18-29 November 26

Panama Canal : United States, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico - Norwegian Sun

Itinerary : Miami, Falmouth, Carthagène, Colon, Limon Port, Harvest Cay, Cozumel, Miami

Panama Canal : United States, Jamaica, Colombia, Panama, Costa Rica, Belize, Mexico - Norwegian Sun

From $1,538

Full board
Full board Port taxes included All Inclusive available

From $1,538

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10 December 26

2 January 27

Other departures

Panama Canal : United States, Aruba, Curacao, Panama, Cayman Islands -

Itinerary : Fort Lauderdale Miami, Oranjestad, Oranjestad, Willemstad, Colon, George Town, Fort Lauderdale Miami

Panama Canal : United States, Aruba, Curacao, Panama, Cayman Islands -

From $1,708

Full board
Full board All Included Offer Available
  • Departure Port : Fort Lauderdale Miami Duration : 12 Days
  • Duration : 12 Days From $1,708
  • Boat :
  • Company : Celebrity Cruises

From $1,708

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Departure :

14 February 28

Panama Canal : United States, Dominican Republic, Aruba, Curacao, Panama, Cayman Islands -

Itinerary : Fort Lauderdale Miami, Puerto Plata, Oranjestad, Willemstad, Colon, George Town, Fort Lauderdale Miami

Panama Canal : United States, Dominican Republic, Aruba, Curacao, Panama, Cayman Islands -

From $1,708

Full board
Full board All Included Offer Available
  • Departure Port : Fort Lauderdale Miami Duration : 12 Days
  • Duration : 12 Days From $1,708
  • Boat :
  • Company : Celebrity Cruises

From $1,708

Discover Offer

Departure :

27 March 28

Panama Canal : United States, Colombia, Panama, Aruba, Curacao, Bonaire -

Itinerary : Fort Lauderdale Miami, Carthagène, Colon, Oranjestad, Willemstad, Kralendijk, Fort Lauderdale Miami

Panama Canal : United States, Colombia, Panama, Aruba, Curacao, Bonaire -

From $1,729

Full board
Full board All Included Offer Available
  • Departure Port : Fort Lauderdale Miami Duration : 12 Days
  • Duration : 12 Days From $1,729
  • Boat :
  • Company : Celebrity Cruises

From $1,729

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Departures :

23 November 26

8 March 27

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

Itinerary : Miami, Carthagène, Colon, Puntarenas, Cabo San Lucas, San Diego, San Francisco, Seattle

Transoceanic : United States, Colombia, Panama, Costa Rica, Mexico - MSC Poesia

From $1,739

Full board
Full board Free for Children * Port taxes included Europe's most modern fleet Kids club
  • Departure Port : Miami Duration : 19 Days
  • Duration : 19 Days From $1,739
  • Boat : MSC Poesia
  • Company : MSC Cruises

From $1,739

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Departure :

6 April 28

What is the best period to cruise the Panama Canal?

With tropical temperatures, it will be pleasant to spend a cruise on the Panama Canal. Temperatures are often around 30°C, so you can tan easily. The period from January to April is the dry season. It is during this period that it is best to go on a cruise on the Panama Canal. The period from September to December is rainy so we recommend you to avoid it.